The diagnostic criteria of chronic liver failure include symptoms, laboratory tests, imaging tests, complications, medical history and other aspects. 1. Symptoms: patients may show abdominal distension, loss of appetite, fatigue, yellowing of the skin, and so on. 2. Laboratory examination: elevated bilirubin, progressive aggravation of jaundice, abnormalities of transaminases and plasminogen activity, and other indicators. 3. Imaging examination: Liver ultrasound and CT examination may reveal abnormalities in liver size and other conditions. 4. Complications: Patients may develop complications such as ascites and hepatorenal syndrome. 5. Medical history: patients may have a history of viral hepatitis B, alcoholic liver, fatty liver, long-term use of hepatotoxic drugs. People with chronic liver failure are advised to consult a specialized doctor in time.