Clinical common skin cysts mainly include sebaceous cysts, epidermoid cysts, popliteal cysts, etc., basically belong to benign lesions. Most of the skin cysts are not serious, if the following conditions occur, the skin cysts need to be operated as soon as possible to avoid serious complications: a larger popliteal cysts, once the popliteal artery and nerves are compressed, the patient can appear lower extremity skin temperature reduction, sensory abnormalities. At this time, if the surgery is not performed as soon as possible, the symptoms of swelling and pain in the lower limbs will gradually aggravate, and cause more serious complications. Therefore, patients need to perform popliteal cyst surgical resection as soon as possible, to avoid the residual cyst wall during the operation, so as to avoid the recurrence of cysts. Second, for sebaceous cysts on the face, once combined with the infection if repeated extrusion may cause local bacteria invasion of the skull, causing intracranial infection. Patients can control the local infection by rubbing Pepto-Bismol ointment, and then perform surgical resection as soon as possible, which can achieve a better therapeutic effect.