Lupus erythematosus is a serious health hazard, especially for young girls, and can be a huge stressor. Early detection of lupus erythematosus will effectively reduce the harm of lupus erythematosus and why it is so. At present, with the continuous improvement of medical level, the detection level of lupus erythematosus is increasing. The detection level is mainly in two aspects: 1. diagnostic examination, such as autoantibody examination, some autoantibodies have good value for the diagnosis of lupus erythematosus. For example, sm antibody has a high diagnostic value. Nowadays, all major hospitals carry out these tests. 2. Tests for early prediction of disease activity and development trend. Such as complement, etc. The significance of these tests lies in the fact that they can warn the occurrence of lupus erythematosus when the diagnostic conditions of lupus erythematosus have not been met. Many of our patients have passed safely because of effective treatment for early detection, stable disease and marriage and children.