Through the previous days, we have learned that Botox is often used to treat the three major wrinkles: forehead lines, Kawasaki lines, and corners of the eyes. Is there nothing that Botox can do for other wrinkles? What is the effectiveness of Botox for other wrinkles? There are two wrinkles that Botox can assist in treating, one is the decollete’s line and the other is the corners of the mouth. The declarative wrinkles are what we usually call nasolabial folds, and Botox alone is not effective in treating them. Botox can only be used as a supplementary treatment. In order to know how to treat the lines, we must first know how the lines are created. Here I have summarized the three main reasons for the production of the lines: 1. The contraction of the corners of the mouth and upper lip nasal muscles will make the lines of the lines appear. 2, due to the downward movement of the fat pad of our upper and middle face, the pressure given is too great and presses out the decrescent lines. 3, due to facial fat atrophy, facial fat and subcutaneous fat skeletal muscle and muscle atrophy, the formation of a state of depression. These three major causes constitute the production of our nasolabial folds, also known as decrepit lines. One of the two major wrinkles that we commonly see in our face is the nasolabial folds, also known as the lines. The other is the marionette line, also known as the corners of the mouth in colloquial language. These two lines are caused by the atrophy of our soft tissues, in addition to the pulling of the muscles associated with them. Therefore, in order to treat these two types of wrinkles, the main treatment is not only muscle relaxation by Botox, but also lifting and filling together to treat these two lines to the best effect. We will talk about face lift and filler next time due to the limitation of space.