The causes of headache and limb pain include over fatigue, infection, emotional disorders, etc. They can be relieved by resting, taking medication and psychotherapy. 1. Excessive fatigue: this will occur after excessive physical activity and over-excitement, and will be recovered after proper rest and sleep, and no treatment is needed. 2. Infection: If the cold is caused by viral infection, there will be fever, headache and muscle pain. At this time, symptomatic treatment, anti-infection, lowering the body temperature, such as oral ibuprofen, acyclovir and so on. 3. Mood disorders: depression, anxiety disorders and other mood disorders, there will be instability of autonomic function, prone to body wandering pain. You can take anti-anxiety and depression drugs, such as sertraline, venlafaxine, etc., also need to cooperate with psychotherapy. When headache and limb pain occurs, it is recommended to consult a doctor in time, after clarifying the cause of the disease, targeted treatment, do not blindly self-medication.