If the stool with purulent mucus, it is considered to be rectal or colitis caused by infection, and possibly inflammatory bowel disease caused by environmental, genetic, immune or infectious factors. If the stool with purulent mucus has a bloody substance, mostly seen in bacterial dysentery, rectal polyps, colon cancer, rectal cancer and other diseases, it is recommended to go to the hospital for timely consultation, clear diagnosis and symptomatic treatment. 1, inflammatory bowel disease: including ulcerative colitis and Crohn’s disease, which can be manifested as an irregular stool, when the lesion occurs in the anorectal segment, the stool has mucus and blood stool. Crohn’s disease is an intestinal inflammation of unknown origin, immune regulation disorders, intestinal flora imbalance, lifestyle changes, high-fat diet can lead to Crohn’s disease; 2, bacteriophageal dysentery: usually stool performance of mucus-purulent blood stool, bacteriophageal dysentery has a great relationship with human resistance, chronic diseases, overexertion, overeating may lead to a decrease in human resistance, bacterial invasion; 3, rectal polyps: Rectal polyps patients excreted stool surface may have more mucus attached, local breakage or when taking hormones, aspirin may lead to bleeding and bloody stools. Age is one of the main causes of rectal polyps, and long-term consumption of a large number of pickled, fried food or meat products, smoking, alcohol abuse, etc. can lead to rectal polyps; 4, cancer: in the early stage of the stool is not obvious abnormalities, with the gradual progress of the disease, there will be blood on the surface of the stool and the phenomenon of mucus blood stool, while the formation of pus and blood stool due to secondary infection of the tumor, the cause is mainly due to unscientific dietary structure The cause of the disease is mainly due to unscientific dietary structure, eating too much high-fat, high-calorie and high-protein food, and insufficient dietary fiber intake, which is prone to cancer.