Spleen and kidney yang deficiency (deficiency of yang qi in the spleen and kidneys) is useful to take Si Shen Wan. Si Shen Wan can treat wu shi diarrhea (diarrhea before dawn) and lack of appetite caused by spleen and kidney yang deficiency. According to Chinese medicine, Yang deficiency of the spleen and kidneys is caused by a weaker body, which is easily invaded by cold, or frequent illnesses that lead to depletion of Yang qi of the spleen and kidneys, or prolonged diarrhea that damages the Yang of the spleen and kidneys, or other deficiencies of the kidneys that involve the spleen and kidneys. Common symptoms include cold fear and cold limbs (fear of cold, cold limbs), prolonged diarrhea and prolonged dysentery. Si Shen Wan, composed of nutmeg, tonic oil, schizandra, schizandra and Wu Zhu Zi, has the effects of warming the kidney, warming the spleen, fixing the intestines and stopping diarrhea. It is used for treating kidney discharge syndrome of spleen and kidney yang deficiency, which is characterized by diarrhea in the fifth day of the month, inappetence, indigestion, prolonged diarrhea, abdominal pain and warmth, lumbar soreness and coldness of limbs, fatigue (mental fatigue and physical weakness), pale tongue, thin white moss, and dull and weak pulse. Avoid cold and greasy food when taking this medicine. Adverse effects of such drugs are not clear, the use of drugs are required under the guidance of a doctor, avoid self-medication.