The cost of a cycle of chemotherapy for multiple myeloma is related to the patient’s condition, chemotherapy regimen and medications. The cost generally ranges from a few hundred dollars to 20,000 dollars. It is important to analyze the specific situation and not to generalize. 1. Vincristine + Adriamycin + Dexamethasone: This method is the traditional treatment for multiple myeloma, and the cost is generally lower, about a few hundred to 1,000 yuan. 2. Bortezomib and lenalidomide combined with dexamethasone: this regimen is more expensive, costing about $20,000 for a cycle. However, different manufacturers, different dosage forms, and different regions have different prices, the specific price should refer to the local hospital level. Diagnosis and treatment should be carried out under the guidance of a physician.