Epinephrine can reduce the excitability and muscle tone of small intestine smooth muscle, and there are two kinds of receptors on small intestine smooth muscle, one is α receptor and the other is β receptor. α receptor has two kinds of excitatory and inhibitory receptors, epinephrine can act on α inhibitory receptor, which can reduce the excitability and muscle tone of small intestine smooth muscle. The mechanism of action is that the activation of epinephrine causes an increase in cAMP synthesis in the myocyte membrane, and cAMP activates the calcium pump in the myocyte membrane and sarcoplasmic reticulum, which decreases the calcium concentration in the sarcoplasm and reduces muscle tone. On the other hand, epinephrine acts on β-receptors, and β-receptor activation induces an increase in potassium and calcium ion efflux, which accelerates membrane hyperpolarization and promotes a decrease in small intestinal smooth muscle tone. Since epinephrine can reduce the peristalsis of the intestine, it is important to pay attention to control your emotions and reduce the secretion of epinephrine in general, which has a protective effect on the function of the gastrointestinal tract.