You won’t get kidney disease from taking hepatitis B medicine, hepatitis B virus may cause kidney disease. Hepatitis B virus infection can cause hepatitis B-associated glomerulonephritis, the exact cause of which is unknown. If patients have unexplained hematuria and proteinuria, renal biopsy and histology are needed for further diagnosis. Recovery is usually achieved by controlling the replication of the hepatitis B virus, and hormone therapy may be given if necessary. Drugs for the treatment of hepatitis B mainly include interferon and nucleotide analogs, and interferon includes short-acting interferon and long-acting interferon. Their adverse effects mainly include flu-like symptoms, bone marrow suppression, induction of autoimmune diseases, causing heart disease, mental abnormalities, anorexia, fatigue, weight loss, hair loss and other symptoms. Nucleotides mainly include lamivudine and adefovir. Adverse reactions mainly include bloating, abdominal pain, muscle and joint pain, and some may have potential risks such as teratogenicity and carcinogenicity. Of course, the incidence of these adverse reactions is relatively low. Patients taking the medication need to follow the doctor’s advice or the recommended dosage in the drug insert, and should not increase or decrease the dosage of the medication without authorization.