There is no clear clinical data indicating how often nasopharyngoscopy can rule out nasopharyngeal cancer, and patients need to undergo relevant examinations regularly. Usually, nasopharyngeal cancer occurs in the anterior wall of nasopharyngeal parietal and pharyngeal crypt, and nasopharyngoscopy can observe that the lesions are nodular or granulomatous, with rough and uneven surface, and are easy to bleed. Due to the atypicality of early lesions, patients need to be diagnosed by pathologic biopsy of nasopharyngeal lesions. However, there is no clear clinical data indicating how often nasopharyngoscopy can exclude nasopharyngeal cancer, and patients can have regular checkups according to their own specific conditions. If necessary, physical examination, EBV serologic examination, magnetic resonance examination of nasopharynx and neck, chest CT, abdominal ultrasound and positron emission computed tomography (PET) examination should be performed to clarify the diagnosis of the disease. In addition, after being clearly diagnosed with nasopharyngeal cancer, patients should strictly follow the doctor’s instruction to carry out targeted treatment, so as to avoid delaying the condition. It is recommended that patients should carry out diagnosis strictly under the guidance of doctors, conduct regular screening and do a good job in protecting themselves.