You can take itraconazole 24 hours after drinking alcohol. Itraconazole Gum is primarily metabolized through the liver and kidneys, while alcohol is similarly metabolized through the liver. Taking the drug within a short period of time after drinking alcohol may aggravate the burden on the liver, so it is generally best not to drink alcohol during or before taking the drug. The metabolism of alcohol in the body generally does not exceed 24 hours, so patients can take itraconazole after 24 hours of alcohol consumption. Itraconazole is a commonly used antifungal infection drug in clinic, mainly used for the treatment of systemic onychomycosis, candidiasis, biphasic fungal disease and so on. Itraconazole may cause dizziness and headache, skin rash, leukopenia and other adverse reactions. It should be contraindicated in people who are allergic to this drug; it is contraindicated in patients with ventricular dysfunction, except for the treatment of life-threatening or serious infections; it is also contraindicated in patients with CYP3A4 substrates; it is also contraindicated in pregnant women. The drug should be used under the supervision of a doctor and should not be used without authorization.