Postoperative recurrence of lung adenocarcinoma includes new lesions in the lung and distant metastatic lesions, and the main treatments depend on the condition of the patient, which mainly include surgical resection, medication, radiotherapy and so on.
1. If there are new lesions in the lung and there are surgical indications, surgical resection can be performed again; if there are no surgical indications, bronchoscopy, percutaneous lung aspiration biopsy and other methods are needed to obtain pathology, and then treatment plan can be formulated according to the type of pathology.
If the pathology is still lung adenocarcinoma, the genetic test will be improved, and if there is a driver gene, then the targeted drug will be used for precise treatment; if there is no driver gene, then systemic chemotherapy and immunotherapy will be used. If the pathology is squamous carcinoma or small cell lung cancer, first-line chemotherapy should be given according to the guideline.
2. If distant metastasis occurs, symptomatic treatment should be given according to specific conditions. If the distant metastatic lesion is an isolated lesion, such as isolated adrenal gland metastasis, isolated brain metastasis, etc., surgical assessment can be made to see if it can be resected.
If the symptoms of some distant metastases are obvious, then the systemic treatment can be carried out after the treatment of the metastases, such as brain metastases with severe intracranial hypertension, then cranial irradiation can relieve the symptoms first, such as spinal column, ribs and other bone metastases, with obvious local pain or compression symptoms, then local radiotherapy can be used to relieve the symptoms first.
Attention: Lung adenocarcinoma recurrence needs to be consulted in hospital as soon as possible. Lung cancer is highly heterogeneous, so it is necessary to make individualized treatment plan after perfecting relevant examination.