Lumbar interspinous ligament edema can be treated with general treatment such as bed rest, avoiding stooping and weight bearing, physical therapy such as hot compresses, medicines such as MaiZhiLing and Celecoxib, and closed treatment if necessary. 1. General treatment: mainly bed rest, avoid excessive flexion of the spine, avoid stooping and weight-bearing, avoid excessive lumbar activity, and wear a waist cuff in daily life. 2. Physiotherapy: hot compresses, massage, microelectrotherapy and other physiotherapy can promote local circulation, promote the absorption of local edema and improve the patient’s symptoms. 3. Drug therapy: such as Mai Zhi Ling and other drugs to reduce edema, pain can be used Celecoxib, Loxoprofen and other non-steroidal drugs, 4. Closure therapy: when the pain is severe and there are obvious pressure points, hormones and local anesthetic drugs can be used for local closure therapy. Lumbar interspinous ligament edema is recommended to go to the hospital in time, early formal treatment, in order to reduce the adverse effects of the disease. The use of drugs need to follow the doctor’s instructions.