Puncture biopsy is to use a puncture needle to take part of the lesion tissue for pathological examination. Through pathological examination, the nature of the lesion can be determined and it is a very important method used to diagnose tumors. For example, for patients with lung cancer, puncture biopsy can be used to determine whether it is squamous lung cancer or adenocarcinoma, small cell lung cancer, etc. If a local mass is found, such as a mass in the thyroid gland or a mass in the breast, puncture biopsy can be used to determine the nature of the mass and then decide the treatment. If the tumor is determined to be malignant through pathological examination, early surgical treatment, followed by radiotherapy or chemotherapy, can prolong the survival time and improve the quality of life of the patient. Through puncture biopsy, the nature of the lesion can be clarified, which plays a key role in the treatment of the disease.