Common causes of knee injury at age 65 include osteoarthritis, patella wear, chronic synovitis, etc. Physiotherapy, medication and surgery need to be selected according to the specific causes. 1. Osteoarthritis: mainly manifested as knee joint pain, which is significant after activity and improves after rest; or pain at rest, which is alleviated after a little activity, but pain can also occur when there is excessive activity. Massage, hot compresses and other physical therapy can be carried out, can also be injected into the joint cavity of sodium hyaluronate, pain relief, difficult to alleviate the arthroplasty can be carried out. 2. Patellar wear: the cartilage surface of the patella rubs against the cartilage surface of the femoral condyle, and the patellar cartilage is worn out, resulting in knee pain and weakness. Strenuous activities of the knee joint should be limited, hot packs or sports rehabilitation, also can take Loxoprofen sodium tablets to relieve patellofemoral inflammation. Conservative treatment is ineffective, arthroscopic surgery can be performed to reduce the wear and tear of patellar cartilage. 3. Chronic synovitis: degenerative changes of the knee joint, joint injury or infection is the cause of the disease, hidden pain in the knee joint, there may be swelling. You can take ibuprofen extended-release capsules to relieve pain, and in severe cases, the synovium can be removed surgically. 65-year-old knee headache may also exist other causes, such as meniscus injury, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, to give targeted treatment or treatment. All of the above drugs should be used under the guidance of a doctor, avoid self-medication.