Patients with acute suppurative appendicitis, combined with gangrene or perforation, or patients with periappendiceal abscesses complicated by diffuse peritonitis are absolute indications for surgical treatment. Because the appendix is a blind end, a secondary obstruction can easily lead to an increase in intraluminal pressure and result in infection. If the obstruction is not effectively relieved, it can also lead to exudation from the plasma membrane surface of the appendix and even to suppuration. Patients may experience significant right lower abdominal pain or typical metastatic right lower abdominal pain with localized signs and symptoms of peritonitis, fever, and in some cases, a feeling of urgency. The most effective treatment is surgery to remove the appendix and remove the infected abdominal cavity, as well as to remove the exudate and pus from the abdominal cavity. Postoperative anti-infective and symptomatic treatment is also required.