Acne belongs to the category of acne in Chinese medicine, and when the diagnosis is dampness, heat, toxicity and stagnation, taking cool blood detoxification granules has a better regulating effect. Cooling blood and detoxifying granules is a kind of common Chinese patent medicine in clinic, which is composed of cypress, gardenia, gypsum, scutellaria, honeysuckle, oyster bark, comfrey, root of white grass, huanghuang, chen, Poria cocos, dragon bone, oyster, licorice. Cooling blood and removing toxins granules have the efficacy of clearing heat, removing dampness, cooling blood and removing toxins, resolving blood stasis and dispersing stagnation. When the diagnosis of acne vulgaris belongs to the evidence of dampness-heat embodiment (dampness and heat evils accumulate with each other in the body), and facial acne is more frequent, yellow and red urination, and constipation is the main symptom, then you can take the drug to adjust the condition. Cooling blood and detoxifying granules need to be correctly used under the guidance of a professional physician’s diagnosis, adverse reactions are not clear, pregnant women need to be prohibited from using this drug. The medication should be taken under the guidance of a professional physician, and should not be taken on its own, in order to avoid delaying the condition.