Maintenance after discharge from hospital with ascites puncture of ovarian cancer should follow the doctor’s prescription to take medicines correctly and pay attention to dietary regulation, and actively treat the primary disease under the doctor’s advice. If ovarian cancer has metastasis or peritoneal implantation occurs. It is easy to be accompanied by ascites. Ascites of such patients are usually yellowish-green or yellow; it is also possible that ascites has red color with obvious blood; if it is mixed with tumor contents or mucus, it will be turbid. If accompanied by a large amount of ascites, it is usually necessary to consider ascites puncture drainage, and the treatment should pay attention to maintenance. 1. Diet: After ascites puncture, attention should be paid to diet, mainly low-salt, high-protein diet, limiting sodium intake, you can choose to consume milk, soybeans, etc. Ovarian cancer also suggests consuming more food rich in unsaturated fatty acids, such as flaxseed oil and seaweed. 2. Treating primary disease: as patients with ovarian cancer are often malnourished, which will lead to low albumin, low vascular osmotic pressure and recurrence of ascites, therefore, we should also treat the primary disease in order to reduce the generation of ascites. 3. Correct medication: if puncture port infection occurs, patients should take antibiotics, such as penicillin, amoxicillin, clindamycin and so on, according to doctor’s prescription. When medication is needed after ovarian cancer ascites puncture, patients should take medication under doctor’s instruction and follow doctor’s advice. Ovarian cancer patients should be treated with surgery under doctor’s advice and combined with chemotherapy after surgery to improve patients’ quality of life. And pay attention to the post-discharge care and go to the hospital for consultation once there is any abnormality.