Generally sperm non-liquefaction can be completely cured. Sperm may be related to bad habits, seminal vesiculitis, acute prostatitis and other reasons, the patient should promptly go to the regular hospital for examination, clear causes for targeted treatment. 1. bad habits: patients should develop good habits, maintain a relaxed and happy mood, avoid long-term late at night, squatting and sedentary behavior, try to do to quit smoking and drinking. In addition, patients should also pay attention to dietary health, eat some rich in vitamins, zinc, selenium food. 2. Spermatozoa: For the spermatozoa caused by spermatozoa can be completely cured, the patient can follow the doctor’s instructions to take antibiotics, such as cefuroxime, levofloxacin, etc.; anti-tuberculosis drugs, such as isoniazid, etc.; glucocorticosteroids, such as prednisone, etc., for treatment, but also for the spermatozoa surgical treatment, to improve the condition. 3. Acute prostatitis: patients should pay attention to quit smoking and alcohol, avoid eating spicy stimulating food, avoid holding urine, sedentary, etc., can follow the doctor’s instructions to take antibiotics, such as ofloxacin, tobramycin, etc.; α-blocker, such as tamsulosin hydrochloride, etc.; non-steroidal anti-inflammatory drugs, such as celecoxib, etc., for treatment, when the disease is cured, the sperm not liquefaction of the symptom may be relieved or eliminated. It is recommended that patients strictly follow the doctor’s prescription of medication, actively cooperate with the doctor’s treatment, develop good habits in life, regular review and so on.