There is a painful sensation in the breast when touched with the hand. First of all, you need to consider mastocytosis caused by mastocytosis is called cystic hyperplasia of the breast, most of which is caused by an imbalance in the level of hormonal disorders in the body, manifested as the symptoms of swelling and stabbing pain in the breast, the pain is aggravated by touching it with the hand, this pain has a clear cycle, will be significantly relieved after the onset of menstruation, most of the pain symptoms disappear. Secondly, acute mastitis can also have painful symptoms. Mastitis is an infection caused by bacteria entering the breast through the ducts of the breast, blood, etc. After the infection, there will be swelling and pain, and the symptoms are aggravated by touching. In addition, the mammary gland is rich in nerve endings and is sensitive to pain. After local soft tissue damage, there will also be painful symptoms when touched by hand, and in severe cases there may be local swelling. So try to go to the hospital to check and determine the cause of the pain.