After taking sertraline, the condition has been stable for more than one year and the anxiety symptoms have improved, you may consider reducing the medication and decide whether to continue the reduction or discontinue the medication depending on the condition during the reduction period. Sertraline is mainly used to treat symptoms associated with depression, including depression accompanied by anxiety, with or without a history of mania. Treatment with antidepressant medication must be adequate in dose and duration and must not be stopped abruptly, otherwise it may easily cause somatic discomfort or lead to relapse. If the depressive symptoms disappear completely, while the social function is fully restored, and the maintenance state treatment is more than one year, without any recurrence of symptoms, the drug dosage can be considered to be reduced. Before reducing the medication, a follow-up visit to the psychiatric department of the hospital is required, and the medication reduction can be started only after the professional assessment and consent of the physician. It is also important to follow the principle of small and slow doses during the reduction period, and not to be too hasty. It should be noted that spring and autumn are the seasons when depression is prone to relapse, so try to avoid reducing or stopping medication in spring and autumn.