Once formed, gallstones have little chance of healing on their own. Gallstones can be treated with general therapy, medication and surgery depending on the situation. Gallstones are stones that form in the gallbladder or bile ducts. The stones usually start as crystals, and as the disease progresses, the crystals gradually calcify and form stones. Normally, once a stone is formed, it cannot go away or heal on its own and will only grow in size. Therefore, treatment is the only way for stones to disappear or heal. For asymptomatic gallstones, general treatment, dietary modification, lifestyle improvement and regular checkups can be taken; During acute attacks, such as severe abdominal pain, fever, nausea and vomiting, medication can be taken to relieve pain and control inflammation, such as ibuprofen capsules and cefuroxime. Symptomatic stones require early surgical treatment, preferring minimally invasive surgical procedures such as laparoscopic cholecystectomy and endoscopic retrograde cholangiopancreatography for stone removal. The probability of self-healing after the formation of gallstones is very small, and it is recommended that active treatment be carried out under the guidance of a doctor.