Azoospermia can be divided into obstructive azoospermia and non-obstructive azoospermia. For patients with obstructive azoospermia, sperm can be obtained through testicular puncture of the epididymis and then IVF can be used to help conception; for patients with non-obstructive azoospermia, donor sperm is recommended to help conception. Option Description: Azoospermia assisted conception option 1: 1. It is suitable for patients with high success rate of surgical sperm acquisition (the doctor will evaluate the patient according to his previous fertility history, testicular development, and sex hormones, etc.). 2. The advantage is that only one surgical sperm retrieval is required on the woman’s egg retrieval day, which reduces the number of sperm retrieval procedures; and the sperm that unites with the egg is freshly retrieved, which reduces the artificial intervention of sperm during freezing. 3. If the sperm cannot be retrieved at that time, the couple can immediately decide to use donor sperm for conception (only hospitals with sufficient sperm source in the hospital and no need to wait for sperm source can provide it without delaying the treatment. 4. The prerequisite for choosing this option is that the couple must consider well in advance and be willing to use sperm donation for conception if sperm cannot be obtained by surgery. Azoospermia assisted conception option 2: 1. For patients who are not prepared to do sperm donation even in the absence of sperm; or for patients who are prepared to do donor insemination in the case of a patent fallopian tube in the female partner. 2. If there is sperm after puncture, the sperm can be preserved by microsperm freezing technology, and the sperm can be thawed when the female partner retrieves her eggs, and there is no need to retrieve sperm again at the time of egg retrieval (Note: In hospitals that do not carry out microsperm freezing technology, it is necessary to surgically retrieve sperm again on the day of egg retrieval. Azoospermia fertility option 3: 1. Both patients with obstructive azoospermia and non-obstructive azoospermia can consider abandoning testicular epididymal puncture and directly performing sperm donation for fertility. 2. Depending on the condition of the female partner, donor insemination or IVF can be used to help conception.