If your knee hurts when you press it, you can consider the following causes: First, synovitis: If it hurts when you press it around the knee, it is usually considered to be caused by synovitis. The pain caused by synovitis is diffuse and does not have a fixed point of pain in the knee, so any pressure around the knee may cause pain. Second, osteoarthritis and meniscus injury: If the pain is felt in a specific part of the knee joint when pressed, such as pain in the medial space of the knee joint, degenerative osteoarthritis of the medial space can be considered, as well as medial meniscus injury, which should be evaluated and judged by MRI and x-ray. Third, other diseases: If the pain is pressed on the posterior side of the knee, it can be considered as popliteal cyst or inflammation and contracture of the posterior ligament, which can cause posterior pain.