The causes of small black particles on the nipple and tingling pain include melanoma, breast cancer, nipple inflammation, nipple eczema and so on. 1. Melanoma: If various factors trigger the abnormal proliferation of melanocytes, these melanocytes can invade the nerves, thus leading to tingling pain. 2. Breast cancer: If various factors lead to a large increase in the number of breast cells, tingling will also occur when these cells press on the surrounding nerves. 3. Nipple inflammation: due to bacterial infection of the nipple, these bacteria damage the skin of the nipple, leading to the proliferation of melanocytes, so small black particles appear. 4. Nipple eczema: when various inflammatory factors stimulate the nipple skin, it triggers the damage of the nipple skin, at this time, small black papules appear around the nipple. Finally, if there is a small black granule on the nipple, and the phenomenon of stinging pain, please consult a doctor in time.