Two hundred years ago (1817), British physician James? Parkinson published a paper that first described the symptoms of Parkinson’s disease. In his book, “Researches Concerning Paralysis of Tremor”, he described the symptoms of Parkinson’s disease in this way: “Involuntary tremor-like movements, accompanied by weakening of the muscles, and in some patients the tremor disappears under conditions of motion or support. The trunk is tilted forward, and after a few steps the walking becomes a trotting motion. If there is no “Parkinson’s” patients around, perhaps we still will not pay attention to this disease, but with the aggravation of population aging, the number of patients with Parkinson’s disease in China is increasing year by year, and it has become second only to tumors, cardiovascular and cerebral vascular diseases, such as serious harm to the health of the elderly, “the third killer! It has become the “third killer” after tumor and cardiovascular diseases that seriously jeopardize the health of the elderly. There are about 4 million Parkinson’s disease patients in the world, China has 2.2 million Parkinson’s patients, more than 1% of the elderly over 60 years old suffer from Parkinson’s disease, that is to say, more than 60 years of age in the population, every 100 there is a Parkinson’s disease patients, however, the public’s understanding of the knowledge and understanding of this disease is far from enough. Three Possible Causes of Parkinson’s Disease To date, the exact cause of primary Parkinson’s disease is not well understood, and this is an issue that is being actively researched by the medical science community. There are several clues, one is related to age, older people are prone to this disease, because after aging, some brain cell degeneration may cause Parkinson’s disease; the second is probably related to environmental pollution, and pesticides, insecticides, herbicides, pollution; the third is probably related to family genetics, if there are some young people onset of disease in their twenties and thirties, and family genetics often have a relationship. . Since there is no clear cause of the disease, it is not possible to do effective prevention. Research has found that drinking green tea, coffee, may be able to reduce the chances of Parkinson’s disease, because the green tea in the tea polyphenols and coffee in the caffeine can increase the content of dopamine in the brain, inhibit the role of neurotoxins, the dopamine neurons have a certain protective effect, and thus may be able to prevent some of the effects of Parkinson’s disease. Typical symptoms of Parkinson’s disease include motor and non-motor symptoms. Motor symptoms can be summarized as “shaking, stiffness and slowness”. Shaking refers to the involuntary shaking of hands, arms or legs; stiffness refers to the muscles become tense, limbs feel stiff, heavy and inflexible when moving; slow refers to slow movements, in daily life, such as dressing, brushing teeth, washing face and other actions become slower, writing smaller and smaller, walking can not open the footsteps, in small steps forward. Non-motor symptoms mainly include smell “failure”, rapid eye movement sleep behavioral disorders, such as nightmares, shouting in bed, etc. In addition, cognitive impairment, as well as insomnia, depression, hallucinations, constipation, etc. may also occur. Treatment of Parkinson’s disease: drugs + surgery + rehabilitation “troika” Diagnosed with Parkinson’s disease, standardized medication is the main means of treatment in the early stages of the patient, Parkinson’s disease patients in the nigrostriatum of the brain in the reduction of dopamine, so the use of levodopa, dopamine agonists, and other medications to supplement dopamine function can be a treatment for the disease. With the progression of the disease and long-term use, the efficacy of the drugs will decline, and there may even be drug-induced motor complications, at which time it is necessary to consider brain pacemaker surgical treatment. In addition, the patient’s weekday exercise rehabilitation training is also very important, rehabilitation training can make the patient maintain good physical condition, delay the progress of Parkinson’s disease and improve the quality of life. The combination of medication, surgery and rehabilitation can maximize the patient’s quality of life close to that of a normal person. In the early stage of Parkinson’s disease, medication can improve symptoms and is the first choice of treatment for early Parkinson’s patients. However, how to choose and match the medications to create a personalized plan mainly depends on the experience and knowledge of the doctor. Therefore, if patients want to adjust their medications, they should do so under the guidance of experienced clinicians, and should not increase or decrease the medication or change the type of medication privately. The China Parkinson’s Disease Treatment Guidelines clearly put forward the concept of comprehensive treatment for motor and non-motor symptoms of Parkinson’s disease, and emphasize the principle of “early diagnosis and early treatment”. Comprehensive treatment includes medication, surgery, exercise therapy, psychological counseling and nursing care. Medication is the first choice and the basic treatment in the whole treatment process, while surgery is an important and effective supplement to medication at specific time windows in the course of the disease.