Migraine headaches usually do not require blood tests. Migraine headache often occurs as a throbbing, severe headache on one or both sides, which may be accompanied by nausea, vomiting and aggravated by acoustic and visual stimuli, and is a chronic neurovascular disease. A clinical diagnosis can usually be made based on the type of migraine attack, family history and neurological examination. CT, CTA, MRI, and MRA of the brain can exclude intracranial organic diseases such as cerebrovascular disease, intracranial aneurysms, and space-occupying lesions. Hematologic tests are usually not necessary. Treatment of migraine is aimed at reducing or terminating headache attacks, relieving accompanying symptoms, and preventing headache recurrence. Treatment includes both pharmacologic and non-pharmacologic treatments. Non-pharmacological treatment is mainly to strengthen the education, help patients to establish scientific and correct concepts and goals of prevention and treatment, maintain a healthy lifestyle, and find and avoid various migraine triggers. Treatment drugs mainly include non-specific painkillers such as non-steroidal anti-inflammatory drugs and opioids, and specific drugs such as ergot preparations and treprostinil. All of the above medications and tests should be performed under the guidance of a medical professional. If any of the above situations occur, please consult a doctor in time for reasonable and standardized diagnosis and treatment.