Tumor Thermotherapy and its Indications

I. What is thermotherapy? Tumor thermal therapy is a new technology for cancer treatment, which is considered as the fifth method of cancer treatment after surgery, radiotherapy, chemotherapy and immunotherapy. Its principle is to use physical methods to heat tissues to a temperature that can kill tumor cells (42.5℃-43.5℃) for 60-120 minutes, so as to destroy tumor cells without damaging normal tissues (safe temperature is 45℃±1℃). Heat therapy can kill tumor tissues, improve body immunity, inhibit tumor metastasis, and have good effect on chest and abdominal fluid and pain caused by cancer, meanwhile, heat therapy combined with radiotherapy and chemotherapy can enhance the therapeutic effect. Classification of thermal therapy: Thermal therapy is divided into whole body thermal therapy, regional thermal therapy and local thermal therapy according to the strengthening range; body surface thermal therapy, body surface – body cavity thermal therapy, body cavity thermal therapy and inter-tissue thermal therapy according to the action site; infrared, ultrasonic, radio frequency and microwave thermal therapy according to the heat source. The mechanism of tumor heat therapy: Malignant tumor grows rapidly and irregularly, so the blood vessels in the tumor have abnormal morphology. They are disorganized, distorted, easily deformed by pressure, and even form thrombosis and embolism. In addition, the blood vessels inside the tumor are mostly composed of monolayer cells, which are fragile and easily broken. It is because of these incompletely developed deformed blood vessels that cannot self-regulate after being heated and the veins cannot speed up the reflux, resulting in local blood stagnation in the tumor, difficulty in heat dissipation in the tumor tissues and obvious increase in temperature. In contrast, when normal tissues are warmed up, blood vessels expand, reflux accelerates, and can dissipate heat faster, so the temperature adjacent to normal tissues is 8-10℃ higher, that is, the temperature of normal tissues rises to 40℃, and the temperature of tumor body can reach about 48-50℃, this temperature has little effect on normal tissues, but it can make tumor cells dead, generally speaking. Generally speaking, the larger the tumor is, the better the effect of thermotherapy is. Indications for systemic thermotherapy: 1. Respiratory system: pleural mesothelioma, lung cancer. 2. 2.Gastrointestinal system: pancreatic cancer, gallbladder cancer, colon cancer, stomach cancer, liver cancer, esophageal cancer. 3.Reproductive system: ovarian cancer, cervical cancer, testicular cancer. 4.Urological system: bladder cancer, kidney cancer. 5.Endocrine system: thyroid cancer, breast cancer, prostate cancer. 6.Hematological system: malignant lymphoma, lymph node metastasis cancer. 7. Chondrosarcoma, fibrosarcoma, smooth muscle, mold spinning leiomyosarcoma, malignant melanoma, body surface tumor, peritoneal metastatic cancer. 8. Advanced tumor intractable pain. 9.Cancerous pleural fluid and ascites. 10.Prevention of tumor recurrence and metastasis. In addition, it has significant effect on prostate hypertrophy, prostatitis and rheumatism arthritis. V. Contraindications to systemic thermotherapy: 1. Body temperature above 38℃. 2, bleeding tendency disease. 3, cardiovascular insufficiency. 4, pulmonary dysfunction. 5, cachexia. 6.Patients with implanted pacemakers. 7, abdominal lesions are prohibited high-power microwave radiation therapy. 8, the head is prohibited radiofrequency fever treatment.