It is usually not recommended that patients often enema, but in the case of intestinal obstruction or drug poisoning, food poisoning, it is possible to perform enemas for treatment. The hazards of enemas are as follows: 1. Enemas can cause dysbiosis in the intestinal tract, which can discharge beneficial probiotics and also cause 2 infections to the intestinal flora, causing dysbiosis. 2. Enemas can cause injury and damage to the intestinal mucosa, usually enemas with mannitol, magnesium sulfate or soap and water, which can irritate and corrode the intestinal mucosa for a long time. There is a certain amount of stimulation and corrosion of the intestinal mucosa, so it is not recommended to carry out high enemas and long-term enemas. 3, the enema because of mechanical operation and rough operation, will cause some damage to the intestinal mucosa and anus.