Hepatitis B virus carriers should be distinguished as true hepatitis B virus carriers or chronic surface antigen carriers, medically divided into two categories, one is called chronic surface antigen carriers, DNA negative and e antigen negative. There is also a group of people who are either e antigen positive or DNA positive, one of the two being positive, which are carriers of the hepatitis B virus. When it comes to carriers of the hepatitis B virus, or carriers of the hepatitis B surface antigen needing treatment, this is a matter of great concern. It can be roughly divided into three categories of carriers, that is, those with normal liver function, not more than 40 units (Beijing standard), the first category of people, presumably the healing is relatively good, basically does not affect the quality of life. The second category of people, the future transaminases to rise, or have some symptoms, affecting part of the quality of life. The third group of people, high-risk groups, such as mother-to-child transmission, the family has five children four children are infected, or three children are infected, the mother 40 years old or 50 years old with liver cancer, or cirrhosis, this is a high-risk groups. The healing of hepatitis B is related to many factors, one important factor is related to family genetics. The development of liver cancer or cirrhosis is not a single factor, it is not only related to the family genetic background, but also to many factors, such as viral load, source of infection, aggressive treatment or not, gender, whether or not to drink alcohol, and many other factors. The physician’s responsibility is to speculate about the possible prognosis of the patient through many indicators and careful clinical examination. We focus on identifying high-risk groups among chronic surface antigen carriers or chronic hepatitis B virus carriers. Some patients with insidious cirrhosis, who have always had a good quality of life, are in their 40s or 50s and have darkened, their spleen has enlarged, their platelets have dropped, and they have reached the stage of cirrhosis. It is the physician’s responsibility to identify these prognostic factors, among which is to follow the family history and know the source of the patient’s infection. Most patients can be presumed to have a source of infection by pursuing their family history, because the infection has a source. There are three types of people, and different people are treated differently. If the patient has no viral replication, her liver function is normal and she is female, and her mother has surface antibodies at the age of 60, the prognosis is definitely mother-to-child transmission, and her daughter will have a very good prognosis, these patients do not need treatment, but they should be followed up regularly, once every six months, at least five tests of liver function, HBV-DNA, and B-mode ultrasound, which can be done in primary hospitals, whether to treat or not to treat, whether antiviral or not. The antiviral effect of carriers is not very good, usually to transaminase elevation before treatment. If necessary, a liver puncture should be done, although the liver function is normal, but the liver function indicators reach the second level, and there are some basis for the development of chronic hepatitis, and there is a virus, this time can also be antiviral.