Advanced kidney cancer generally adopts comprehensive treatment, palliative treatment and symptomatic treatment, and can take targeted drugs, immunotherapy drugs, pain relieving drugs and so on, to improve the quality of life and prolong the survival time of patients. For advanced renal cancer (metastatic renal cancer), most patients have lost the chance of surgical resection, so they can consider using targeted therapy drugs or immunotherapy drugs, which can generally control the tumor progression and improve the prognosis of patients.Targeted therapy mainly includes sunitinib, sorafenib, axitinib, bevacizumab and so on, while immunotherapy includes nabilizumab combined with ipilizumab, leukocidin, etc. If severe pain occurs, you may take targeted drugs and pain relief drugs to improve the quality of patients’ life and prolong the survival time. If severe pain occurs, drugs such as ibuprofen can be taken to relieve pain and improve patients’ quality of life. In conclusion, the medication of kidney cancer is related to pathological subtype, stage, symptoms, personal physical condition, etc. It is recommended to go to regular hospitals to evaluate the condition and follow the doctor’s instruction to cooperate with the treatment, and follow the doctor’s instruction strictly in the medication treatment, and don’t use the medication on your own, so as to avoid the delay of the condition.