Urticaria is not a low immune system, but an immune dysfunction. Urticaria is a common clinical allergic disease of the skin and mucous membranes, characterized by an allergic limited edematous eruption with severe itching. Most of the causes are food, drugs, infections, inhalation such as pollen, physical hot and cold stimuli, there are hereditary, secretion system diseases, but also mental factors, mental fluctuations, mental stress, etc. caused by insects can also cause urticaria. The clinical cause of urticaria is complex and can be caused by a variety of endogenous or exogenous complex factors, and the diagnosis is not difficult. The clinical manifestation is the sudden appearance of wind clusters on the skin, which may subside on their own after a few hours, not exceeding 24 hours, occurring in batches and sometimes repeatedly several times a day. Treatment is with antihistamines, such as desloratadine, levocetirizine, and olopatadine. For heavier weight and unsatisfactory treatment, the drugs can be doubled.