Special attention needs to be paid to taking insulin once a day, usually with long-acting insulin (the common ones are glucagon and detriment insulin), as well as to diet and lifestyle. Glycine insulin is a recombinant human insulin analogue with the characteristics of smooth, no peak, and long duration of action. After subcutaneous injection, a microscopic precipitate is formed due to the neutralization of the acidic solution, and a small amount of glycemic insulin can be released continuously. Dieter’s insulin is a long-acting insulin, a colorless, clear liquid, and its action is mainly to lower blood glucose, especially to supplement basal insulin, which can lower fasting blood glucose, and it is a long-acting insulin analog. It is recommended to pay attention to a light diet, avoid high sugar and high fat food, pay attention to rest, avoid staying up late, and have regular checkups. The precautions for taking insulin once a day vary depending on the patient’s medication regimen and individual constitution, and it is recommended to consult an endocrinologist.