The five items of hepatitis B are what we usually call the two pairs of half, while the five items of hepatitis B qualitative refers to the clinical detection of the five items of hepatitis B is negative or positive, the qualitative method has been less used in recent years. Nowadays, more methods are used to quantify hepatitis B. Quantification refers to the concentration of surface antigen or surface antibody, as well as the concentration of e antibody and core antibody, which can be measured with the current testing reagents. After the concentration is detected, it can be used as a reference indicator during antiviral treatment.