Decreased tone of the lower sphincter of the esophagus is a major symptom of scleroderma esophagus, which is mainly a scleroderma that causes functional changes in the esophageal sphincter of the patient. Scleroderma is primarily a connective tissue disease that can lead to fibrous tissue or small blood vessels in multiple organs, and in some cases can accumulate to the point of accident and lead to ischemia in the smooth muscle of the esophagus, resulting in collagen deposition in the patient’s submucosa, and the formation of fibrosis. The normal function of the esophagus is affected. Decreased lower esophageal sphincter function can be caused by a variety of factors, the first of which can be related to the patient’s immune factors, for example, when the patient has some autoimmune disease, which can lead to the presence of autoantibodies in the patient’s serum, which may lead to decreased lower esophageal sphincter function. Other causes may also lead to decreased lower esophageal sphincter function, such as abnormal synthesis of collagen fibers, and vascular factors are also an important factor in decreased lower esophageal sphincter function. For patients, it is important to pay attention to the diagnosis. Generally speaking, when the lower esophageal sphincter function decreases, the main clinical manifestation of the patient is difficulty in swallowing, sometimes accompanied by nausea and vomiting, and sometimes there may be a feeling of fullness in the abdomen. Note: Decreased lower esophageal sphincter function is a clinical manifestation of scleroderma. Generally speaking, when patients have lower esophageal sphincter dysfunction, they can be diagnosed as having scleroderma.