The causes of enlarged lymph nodes in children may be infections, tuberculosis, blood diseases, etc., which can be treated by anti-infection, anti-tuberculosis and chemotherapy. 1. Infection: when children have upper respiratory tract infections, oral ulcers, otitis media and other infections, it may lead to localized lymph node enlargement, which can be treated with relevant antibiotics such as azithromycin according to the pathogens causing the infection. 2. Tuberculosis: Children infected with Mycobacterium tuberculosis may lead to enlarged lymph nodes, which can be treated with anti-tuberculosis drugs such as isoniazid and rifampicin. 3. Blood diseases: acute lymphoblastic leukemia may cause generalized lymph node enlargement in children, which can be treated with vincristine, methotrexate and other drugs. If children have enlarged lymph nodes, they should seek medical treatment in time, and relevant drugs should be used under the guidance of doctors.