The diagnosis of pancreatic true cyst needs to be analyzed comprehensively according to the patient’s clinical manifestations, auxiliary examinations and other information. 1. Clinical manifestations: patients may have nausea, abdominal distension, abdominal pain and other symptoms. Symptoms caused by small cysts may be mild, while larger cysts may compress the common bile duct and cause jaundice. A mass may be felt on palpation of the abdomen, and its surface is relatively smooth and its borders are clear. True and false cysts of the pancreas have similar symptoms and need to be differentiated by imaging. Clinical manifestations are helpful in the initial diagnosis of pancreas-related diseases. 2. Auxiliary examination: when doing abdominal ultrasound examination, there can be seen a multicompartmental echogenic area in the pancreas, and the cyst wall and septum are thicker. Abdominal plain film examination can be made, in the pancreas can be seen in the mass of tissue shadow, if the cyst is complicated by bleeding and infection can be seen in the calcified foci of shadow. Abdominal CT examination can help to identify true or false cysts, CT can see the location of the cyst, mostly located in the pancreatic parenchyma, the thickness of the cyst wall, smooth or not. 3. History of pancreatitis: Patients with a history of acute pancreatitis are more likely to be considered pseudocysts. Patients should be diagnosed under the guidance of a doctor and should not make blind judgments on their own to avoid delays.