New coronavirus keeps mutating because the new coronavirus is prone to errors during replication and amplification, resulting in replication that is different from the previous virus. Neocollins is a respiratory infection caused by a new type of coronavirus infection, and has evolved over time with a number of variants as it spreads through the population, such as variant strain B.1.1.7, variant strain B.1.351, variant strain P.1, and so on. The main reason for the continuous mutation of the new coronavirus is that the new coronavirus is an RNA single-stranded virus, which is not as stable as the double-stranded DNA virus, and is prone to errors during replication and amplification, leading to mutation of the replicated offspring virus, such as the mutated strains with large distinguishing features, which are easy to be monitored, and to be given new definitions from the medical point of view and given the names of the corresponding mutated strains. During the epidemic, pay attention to reduce going out, avoid going to places where people gather, wear masks when going out, and get vaccinated in time to reduce the chance of infection.