Broadly speaking, there are many major screening programs included, such as screening for fetal chromosomal abnormalities, non-invasive DNA blood sampling, etc. The cost ranges from $100 to $3,000, and varies from program to program. The cost of having a 4D ultrasound is about $300, and the best time for the examination is between 22 and 26 weeks of pregnancy. An NT ultrasound of the fetus should be done between the 11th and 136th day weeks of pregnancy, and the cost is about $100.3 A Down’s syndrome screening blood draw is needed at each of the 9th to 13th and 16th to 19th weeks of pregnancy, and the total cost is about $200 to $300. This is followed by two non-routine screening programs, including: non-invasive DNA blood sampling at 16~24 weeks of pregnancy, which costs around $2,000; and amniocentesis at 18~24 weeks of pregnancy, which costs around $3,000. All in all, it costs about 100 to 3,000 yuan per time to do a major screening, and the specific items need to be chosen by the doctor according to the condition.