The pre-terminal state of lung cancer patients varies from patient to patient and is not uniform. The most common symptom of most terminal patients is chronic wasting and cachexia. Patients often have long-term wasting at this time, so they are extremely thin, poor in spirit, depressed, or even in a shallow coma, with a skin and bone appearance. For example, patients with brain metastases will have severe headaches, and patients with bone metastases will have pain in the bones of the metastases. In addition, before the end of life, the patient will also experience cardiopulmonary failure, which is characterized by difficulty in breathing, sputum obstruction, and confusion, and this condition usually becomes more serious at night, and in the end, there may even be hemorrhage, mental abnormalities, and the performance of hands constantly lifting the quilt.