Bone marrow aspiration (BMA) is necessary for the diagnosis of leukemia, and it can not only make a clear diagnosis of leukemia, but also determine the type of leukemia, so it is necessary to do BMA. 1. Bone marrow aspiration is the gold standard for leukemia diagnosis, which refers to the invasive technique of obtaining bone marrow specimens for cytology and immunology, etc. It can not only clearly diagnose leukemia, but also determine the specific type of leukemia through the cell types and ratios, so as to carry out targeted treatments and treatments. For example, acute myeloid leukemia is treated with chemotherapy with drugs such as cytarabine and Zoerythromycin. 2. In addition, bone penetration examination can also be used to determine the efficacy of treatment observation and determine the prognosis, so for those who suspect that the disease needs to be clearly diagnosed, bone penetration must be done to confirm the diagnosis. Bone penetration needs to be operated by professional physicians, and when discomfort occurs, it needs to be actively diagnosed and treated.