Oral mucous membrane fibrosis is a chronic disease, and if it is not cancerous, it is not life-threatening and will not shorten the life span. Oral mucous membrane fibrosis is often triggered by long-term stimulation of oral mucous membrane such as chewing betel nut, which makes the oral mucous membrane become hard, white and lose elasticity, and it is conscious that there is a burning sensation in the oral cavity, and it is painful to eat stimulating food. Generally speaking, after the disease, if the stimulation of oral mucous membrane is stopped or surgical treatments are conducted, so that the situation of the oral cavity is no longer malignant, the disease of oral mucous membrane fibrosis will not affect the life expectancy. If oral fibrosis disease occurs cancer appears oral cancer, generally after the disease can survive for five years, after the oral fibrosis suggests to stay away from stimulating factors such as chewing betel nut, etc., and at the same time, regular re-examination to prevent cancer.