Osteogenesis imperfecta is an abnormality or defect in the metabolism of collagen in the body due to genetic factors. The disease usually causes lesions in the bone, skin, sclera, and teeth, and is often characterized by a triad of symptoms, including bluish sclera, underdeveloped teeth, and generalized osteoporosis with pathologic fractures. Patients are often seen with pathological fractures, which can occur with minor external forces, and some patients are born with fractures in the lower extremities or clavicle, for example. The diagnosis of this type of disease is not difficult, the treatment is relatively more difficult, because although the fracture is easy to deal with, but the patient can undergo a slight external force, and then a new fracture can occur, and with the repeated and continuous occurrence of fractures, it may lead to serious disability and even life-threatening.