The dangers of high neonatal bilirubin are manifested in severe cases that can cause bilirubin encephalopathy, also called nuclear jaundice, which can cause damage to the baby’s nervous system with neurotoxicity in specific areas of the brain, especially the basal nucleus, pons and cerebellum. Once nuclear jaundice develops, it can be severe enough to kill the baby. The main sequelae in surviving babies are abnormal brain function, such as physical dysfunction, manifested as choreographic tardive dyskinesia, and high frequency neurological deafness. Then there are signs of mental retardation, which can manifest as language learning difficulties, and in some cases, even paralysis. Parents are advised to take their babies to the hospital to find out the cause of high bilirubin values and to give symptomatic treatment to avoid bilirubin encephalopathy, which can cause irreversible harm to the baby.