Newborns with jaundice of 300umol/L or more and a percutaneous jaundice value of 17mg/dL need timely intervention, blue light irradiation to reduce jaundice, intravenous application of albumin to reduce free bilirubin; jaundice caused by hemolysis requires the application of gammaglobulin to block hemolysis, and unsuccessful treatment requires blood exchange therapy. newborns with jaundice values of more than 3 days 17mg/dL, blue light irradiation is recommended to reduce jaundice, bilirubin level is above 300umol/L, jaundice degree is relatively high need to improve the cranial magnetic resonance examination, check whether there is bilirubin encephalopathy and intracranial hemorrhage may be.