If lateral rib compression neuralgia occurs, it needs to be treated with medication or surgical intervention, depending on the cause. If left intercostal neuralgia occurs without other symptoms, it is just simple intercostal neuralgia, which may be manifested as a burning sensation, electric shock-like or painful sensation in the skin of 1 or 2 intercostals, distribution. The treatment mode can follow the doctor’s advice to choose gabapentin and pregabalin for intervention, which can effectively relieve the clinical symptoms. If left intercostal neuralgia is present, it may be herpes zoster on the left side, caused by herpetic neuralgia. If it is in the acute phase, antiviral therapy is needed, and ganciclovir and anti-inflammatory dexamethasone are used as prescribed. At the same time can be given nutritional nerve-related nerve growth factor and other drugs, early intervention treatment, oral pain medication, such as carbamazepine, gabapentin, etc., take the drug according to the doctor’s instructions, do not use arbitrarily. If left intercostal neuralgia occurs, the cause of the occurrence of chest wall tumors or caused by the chest wall, can follow the doctor’s advice for chest wall mass removal, pain relief. If the lateral rib compression neuralgia occurs, it is recommended to consult a doctor in time, complete the examinations, clarify the cause of the disease, and follow the doctor’s instructions for the cause of the intervention.