In the middle of the night, a lot of sweating in the chest, may be a physiological phenomenon, may also be the symptomatic manifestation of certain diseases, such as hyperthyroidism, tuberculosis, etc., to exclude the physiological causes, it is recommended that the patient go to the hospital in a timely manner, to clarify the cause of the disease. 1. Physiological factors: due to external interventions, such as being in an environment with too high a temperature, or the quilt is too thick, the phenomenon of sweating in the anterior chest in the middle of the night can occur, which is a physiological phenomenon, and sweating can be relieved by lowering the temperature of the external environment in general. 2. Pathologic factors: (1) hyperthyroidism: due to the increased secretion of thyroid hormones, resulting in increased sympathetic excitability and accelerated metabolism, patients may experience excessive sweating, heat intolerance, fatigue, weakness, emaciation, irritability and insomnia, weight loss and other high metabolic syndrome, which can cause middle of the night anterior chest sweating. (2) Tuberculosis: a chronic infectious disease caused by tuberculosis bacilli, patients may show low fever in the evening or afternoon, accompanied by night sweats, fatigue, loss of appetite, etc., and when the lesion expands, high fever, cough, chest pain or generalized exhaustion and other symptoms may occur. If the patient recurrently appear in the middle of the night before the chest constantly sweating, should promptly go to the hospital, by the doctor to clarify the cause of the disease, give targeted treatment.