Migraine can be treated with ibuprofen. Migraine is a common type of primary headache in clinical practice and belongs to the category of neurovascular headache. It is characterized by episodic, mostly unilateral, moderate to severe throbbing pain, which is often accompanied by nausea, vomiting, phonophobia and photophobia. For mild to moderate migraine attacks, you can start by taking non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen, naproxen, and diclofenac sodium. If the headache is not relieved, opioids, such as pethidine, can be used. If a headache attack is followed by a headache that is not responding well to any of the above medications, or if the pain is moderate to severe, specific medications for the treatment of migraines can be used directly, including 1) ergot-type preparations, such as ergotamine and dihydroergotamine, and 2) treprostinil-type preparations, such as sumatriptan.