The gallbladder pressure point is mainly located in the right side of the midclavicular line and the intersection of the rib arch, clinically, if there is acute cholecystitis, the gallbladder pressure point is positive, that is, the Murphy’s sign is positive, so the gallbladder pressure point is positive is Murphy’s sign is positive. If there is a positive Murphy’s sign in the clinic, it can be diagnosed as acute cholecystitis, and the main reason is that the inflammation of the gallbladder is heavy, there is oozing around the gallbladder, and the inflammation stimulates the peritoneum so that there will be pressure pain at the location of the pressure point of the gallbladder. Positive Murphy’s sign suggests that the inflammation of the gallbladder is still relatively heavy, and old and frail patients may have perforation of the gallbladder, so it is necessary to pay enough attention.